Background and Objectives: The husk fibers of coconut (Cocos nucifera) are reported to be used by people of rural areas of South India for daily cleaning their teeth.As the beneficial effects of this Advanced Wound Care - Composites plant material, with respect to antimicrobial properties against common cariogenic bacteria, are not scientifically p
High-throughput gene expression profiling of memory differentiation in primary human T cells
Abstract Background The differentiation of naive T and B cells into memory lymphocytes is essential for immunity to pathogens.Therapeutic manipulation of this cellular differentiation program could improve vaccine efficacy and the in vitro expansion of memory cells.However, chemical screens to identify compounds that induce memory differentiation h
Case report: Neuroendocrine breast carcinoma with a germline EGFR T790M mutation
BackgroundThe epidermal growth factor receptor (EGFR) p.Thr790Met (T790M) mutation was discovered as a resistance mechanism in patients with lung cancer treated with first- and second-generation tyrosine kinase inhibitors.Further studies revealed the EGFR T790M mutation in treatment-naive non-small cell lung carcinoma (NSCLC) and as a rare germline
Study on water inrush failure mode of karst tunnel based on three-dimensional discrete-continuous coupling
During the construction of karst tunnel, it is difficult to avoid approaching the cavern, even high pressure water cavern.Water inrush damage very easily Table causes safety accidents and would have irreversible impact on the tunnel.The study on damage mode is conducive to solving problems related to karst tunnel safety and has certain significance